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Cambridge IGCSE Biology · 0610
Chapter 2: Organisation of the organism
Cell structure
All living things are made of cells, which are produced by the division of existing cells.
- Similarities between animal and plant cells: Both contain a nucleus, cytoplasm, mitochondria, ribosomes, and a cell membrane.
- Differences: Plant cells contain a cell wall, a vacuole, and chloroplasts. They also have a more regular shape and are generally larger than animal cells.
Bacterial cells
Bacterial cells are unicellular and differ significantly from plant and animal cells.
- Features: They contain a cell wall, cell membrane, cytoplasm, and ribosomes.
- Genetic Material: They lack a nucleus; instead, they have circular DNA (a loop of DNA) that floats in the cytoplasm and small rings of DNA called plasmids.
- Key Differences: They lack mitochondria and chloroplasts. Their cell wall is made of peptidoglycan, rather than cellulose.
Exam Traps
- Bacteria have no nucleus, no mitochondria, and no chloroplasts — do not label circular DNA inside a nucleus.
Functions of cell structures
- Cytoplasm
- A jelly-like material in which reactions occur; it contains structures like ribosomes and vesicles.
- Cell membrane
- A thin membrane that surrounds the cell and controls the entry and exit of substances.
- Nucleus
- Contains genetic material in the form of DNA which codes for proteins; it is also the site of DNA replication.
- Ribosomes
- The site of protein synthesis.
- Mitochondria
- The site of aerobic respiration, providing energy for the cell to function.
- Chloroplasts (Plants only)
- The site of photosynthesis, allowing plants to convert light energy into glucose.
- Vacuole (Plants only)
- A fluid-filled sac containing mineral salts, sugars, and pigments; it helps support the cell.
- Cell wall (Plants only)
- Made of cellulose; it gives the cell structure and prevents bursting.
Specialised cells
Cells are adapted to carry out particular functions:
- Ciliated cells
- Found lining the trachea and bronchi; they have hair-like projections called cilia that move together to transport mucus, dust, and bacteria upwards to the throat.
- Root hair cells
- Adapted with a large surface area to speed up the rate of osmosis and mineral ion uptake in plants.
- Palisade mesophyll cells
- Found at the top of leaves; they are tall, closely packed, and contain many chloroplasts for maximum photosynthesis.
- Neurones
- Nerve cells adapted to rapidly transmit electrical impulses. They are myelinated for insulation and have branched dendrites to receive impulses.
- Red blood cells
- Contain haemoglobin to transport oxygen. They have a biconcave shape for a large surface area and no nucleus to make more space for oxygen.
- Sperm cells (Gametes)
- Have a tail for movement, many mitochondria for energy, and digestive enzymes in the acrosome to penetrate the egg.
- Egg cells (Gametes)
- Have nutrients in the cytoplasm for the embryo and a jelly coat that changes after fertilisation to prevent other sperm from entering.
Levels of organisation
The body is organised into increasingly complex levels:
- Cell
- The basic building block of all living organisms.
- Tissue
- A group of similar cells working together to carry out a particular process.
- Organ
- A group of tissues working together to carry out a specific function.
- Organ system
- A group of related organs working together to carry out functions in the body.
- Organism
- Formed by organ systems working together.
Size of specimens
To calculate the size of a specimen viewed under a microscope, use the following formula:
Magnification = Image size
Actual size
Actual size
- Units: Image size should be measured in millimetres (mm).
- Conversion: To convert from millimetres to micrometres (μm), multiply by 1000 (1 mm = 1000 μm).
Examiner Report Insights
- Magnification = image size ÷ actual size; rearrange the formula rather than memorising only one form.
Exam Traps
- Convert millimetres to micrometres by multiplying by 1000 before substituting into the magnification formula.
- Magnification has no units — it is a ratio, so do not write mm or µm in the final answer.
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